Alzheimers Disease

This essay has a total of 729 words and 3 pages.

Alzheimers Disease

Alzheimer's Disease is a progressive and irreversible brain disease that destroys mental
and physical functioning in human beings, and invariably leads to death. It is the fourth
leading cause of adult death in the United States. Alzheimer's creates emotional and
financial catastrophe for many American families every year. Fortunately, a large amount
of progress is being made to combat Alzheimer's disease every year. To fully be able to
comprehend and combat Alzheimer's disease, one must know what it does to the brain, the
part of the human body it most greatly affects. Many Alzheimer's disease sufferers had
their brains examined. A large number of differences were present when comparing the
normal brain to the Alzheimer's brain. There was a loss of nerve cells from the Cerebral
Cortex in the Alzheimer's victim. Approximately ten percent of the neurons in this region
were lost. But a ten percent loss is relatively minor, and cannot account for the severe
impairment suffered by Alzheimer's victims. Neurofibrillary Tangles are also found in the
brains of Alzheimer's victims. They are found within the cell bodies of nerve cells in the
cerebral cortex, and take on the structure of a paired helix. Other diseases that have
"paired helixes" include Parkinson's disease, Down's Syndrome, and Dementia Pugilistica.
Scientists are not sure how the paired helixes are related in these very different
diseases. Neuritic Plaques are patches of clumped material lying outside the bodies of
nerve cells in the brain. They are mainly found in the cerebral cortex, but have also been
seen in other areas of the brain. At the core of each of these plaques is a substance
called amyloid, an abnormal protein not usually found in the brain. This amyloid core is
surrounded by cast off fragments of dead or dying nerve cells. The cell fragments include
Continues for 2 more pages >>