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Bacterophage therapy vs. antibiotics in medicine
In this paper I will be discussing bacerophage therapy. The goal of this paper is to explain bacterophage therapy and how is beneficial and how this therapy can hanve some down sides to it.
Bacterophages are viruses that attack certain bacterial cells without doing any harm to the animal cell. Phage therapy works by the recognizing a bacterium then it attaches its receptors on to the bacterial cell which allows the phage to attach itself which leads to the phage injecting the bacterium with the genetic material. After taking over the bacterium the phage produces es multiple phages which leads to the phage killing the targeted cell. As the targeted cell dies the phage multiples multiple times to make sure that there is no bacteria left behind.
Bacterophage therapy has a lot of advantages that helped the medical field in general. Bacterophages are parasites that target certain bacterium unlike antibiotics. They help us maintain the good bacteria we have. This type of therapy increases wherever its needed and target it immediately unlike antibiotics it targets all the bacteria in the body and sometimes have prescribe it more than once to become effective.
Bacterophage therapy has many pros. One of them is the auto dosing, during that process phages are capable of increasing that number wherever it's needed to target the hosts. Its called auto dosing because phages keep multiplying until it's a satisfactory number to kill that cretin bacterium. Applying the phage in a single dose that's one of the most important advantages because that one dose of that cretin phage can kill a lot of bacteria which makes it very significant. this method achieves satisfactory only from a single dosage or less frequent because its more effective than antibiotics to reach its goal.
Another benefit is that phages have rapid discovery. Phages against many bacteria have been discovered and these discoveries come from waste that has a concentration of bacteria also they are discovered from swage .( ) another benefit is the low nviornmental impacts it makes and that's because of their makeup. Phage are made up of nuclic acid and proteins and pooses a narrow host range unlike antibiotics they are very broad and have a wide range. With all that phages are rapidly effected because they get effected by the enviernment and they are easily inactiviated due to their sensitivity to sunlight and temperature and other factors. Also they environmentfriendly because their cost is very low because of the production process and the cost has been decrsing as technology improves.
However it does not mean that bacterophages are perfect and have no cons they do infact that not all phages make good therapeutics. The use of temperate phages as therapeutics is problematic due to a combination of display of super infection immunity which converts phage-sensitive bacteria into insensitive ones, and the encoding of bacterial virulence factors, including bacterial toxins .
Another down side is that the problem of narrow host range because no antimicrobial which has the characteristics of selective toxisisty will possible effect all microbial targets. Also they are not unique pharmsugacals because they protein-based, live-biological agents that can potentially interact with the body's immune system, can actively replicate, and can even evolve during manufacture or use, but are far from unique in these regards. For example, many protein-based pharmaceuticals can stimulate immune systems, antibiotics that lyse bacteria will release bacterial toxins in situ, and live-attenuated vaccines both actively replicate and evolve including within the context of infecting body tissues . Protein-based drugs, chemical antibiotics, and whole vaccines have previously been approved for use despite these various properties. It therefore stands to reason that phage-based pharmaceuticals should not be disqualified for possessing similar attributes.
In conclution phages have a lot of properties that makes them a good alternative to chemical antibiotics because all of the other concerns about phage therapy are manageable and they can be managed by selecting the right selection of the phage and the proper understanding of phage therapy and becoming fimolar with it will help phage therapy lead to a decrease in the use of antibiotics. Because we are in aera where antibiotics resistant
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